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ＢＡＬＢ／ｃ小鼠接受１０４０ｃＧｙ６０Ｃｏγ射线腹部照射后，采用不同来源的ＲＮＡ、不同的注入剂量、途径、时间和次数等因素，研究外源ＲＮＡ对空肠肠腺存活率的影响。结果表明：（１）不同来源的ＲＮＡ均可明显提高受照小鼠的肠腺存活率。（２）酵母ＲＮＡ的注入剂量与肠腺存活率之间呈一钟形曲线，局部肠腔注入的最适剂量为４０～６０μｇ／小鼠，腹腔和肌肉注入时均为８０μｇ／小鼠。（３）采用从（静脉、腹腔、肌肉和皮下）不同途径注入酵母ＲＮＡ，均可显著提高受照小鼠的肠腺存活率，其中静脉注入效果最佳。（４）照射后小鼠的肠腺存活率随注入酵母ＲＮＡ时间的推迟而降低，两者在半对数坐标上呈线性关系。（５）小鼠于照射后６ｈ内１次注入ＲＮＡ，即可生效，多次注入并不增加其疗效。
BALB / c mice receiving 1040cGy60Coγ ray abdomen irradiation, using different sources of RNA, different injection dose, route, time and frequency and other factors to study the exogenous RNA on the survival rate of jejunum gut. The results showed that: (1) RNA from different sources could significantly improve the survival rate of gut gland in irradiated mice. (2) The bell-shaped curve between the injection dose of yeast RNA and the survival rate of gut gland was 40 ~ 60μg / mouse for local intestinal injection and 80μg / mouse for both intraperitoneal and intramuscular injection. (3) By injecting yeast RNA (intravenous, intraperitoneal, intramuscular and subcutaneous) different ways can significantly improve the survival rate of irradiated gut gland, in which the best effect of intravenous injection. (4) After irradiation, the survival rate of intestinal glands in mice decreased with the delay of infusion of yeast RNA, and the linear relationship was found in the semi-logarithmic coordinates. (5) The mice injected with RNA once within 6h after irradiation, can take effect, multiple injections did not increase their efficacy.