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目的:探讨高血压、高血糖对2型糖尿病肾病(DN)尿蛋白排泄量(UPE)的影响.方法:测定47例DN伴高血压患者与40例不伴高血压DN患者的24小时的UPE.每组又按血压、血糖控制理想与否分为A,B,C,D4小组,并比较了各小组的UPE变化.结果:高血压、高血糖DN组UPE显著地高于高血糖DN组(P＜0.01).A,B,C,D各组UPE分别是(776±322)、(2614±1640)、(678±180)、(1309±465)MG/24H.B∶C,B∶A,B∶D,D∶A有显著差异(P＜0.01或0.05),A∶C,D∶C无显著差异(P＞0.05).结论:高血压、高血糖共同影响着尿蛋白排泄量.严格控制高血压、高血糖可减少UPE,早期严格控制血糖能延缓或逆转疾病进程,但在显性糖尿病肾病期,控制血压更为重要“,”Objective: To study the effects of the hypertension and hyperglycemia on 24h urinary protein excretion (UPE) in nephropathic type 2 diabetes Methods: UPE was measured in 87 nephropathic diabetes, with 47 cases associated with hypertension (HDN) and 40 normotensive patients (NDN) Patients were subdivided into four groups (a,b,c,d) according to the levels of blood pressure and glucose control UPE was compared among these subgroups Results: ...