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目的：为探讨大剂量胸腺肽对慢性乙型肝炎（ｃｈｒｏｎｉｃｈｅｐａｔｉｔｉｓＢ，ＣＨＢ）的治疗作用与免疫调节的关系；方法：按诊断标准选择８０例ＣＨＢ患者，治疗组５０例用大剂量胸腺肽１６０ｍｇ每日静滴一次，２个月后改为每周二次，疗程三个月；对照组３０例用护肝降酶药常规治疗３个月；结果：发现两种疗法，ＡＬＴ的复常情况无明显不同（Ｐ＞００５），治疗组ＨＢｅＡｇ和ＨＢＶＤＮＡ阴转率及ＨＢＶＤＮＡ下降率，免疫学指标的改善均优于对照组（Ｐ＜００５）；结论：表明大剂量胸腺肽对ＣＨＢ有治疗作用，并且与免疫调节作用有关
Objective: To investigate the therapeutic effect of high-dose thymosin on chronic hepatitis B (CHB) and its relationship with immune regulation.Methods: Eighty CHB patients were selected according to diagnostic criteria. 50 patients in the treatment group were treated with high dose thymosin 160 mg daily Once a month, two months later twice a week, the course of treatment for three months; control group of 30 patients treated with HEPt routine treatment for 3 months; Results: Found that the two treatments, ALT normalization no significant difference (P > 005), the treatment group HBeAg and HBVDNA negative rate and HBVDNA decline, the improvement of immunological indicators were better than the control group (P <0 05); Conclusion: The high dose of thymosin on the treatment of CHB, and And immune regulation related