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目的探讨腔外型胃肠道间质瘤的MSCT表现及诊断价值。方法回顾性分析经手术和病理证实的腔外型胃肠道间质瘤患者50例，术前均行螺旋CT平扫加两期或三期增强扫描。结果本组50例GIST中，肿块均向腔外生长，发生于胃15例；发生于小肠15例，其中十二指肠6例，空肠6例，回肠3例；发生于乙状结肠3例，直肠3例；大网膜3例，肠系膜3例，腹膜后5例，盆腔4例，膀胱2例。完全实性12例，实性并坏死30例，实性并出血24例，同时合并出血、坏死或囊变者18例，实性并钙化者3例，积气6例，CT表现40例边界清晰,缘分叶19例，转移3例，其中淋巴结转移4例，复发3例；增强扫描，肿瘤轻度到明显强化，动脉期强化明显者，静脉期及延时期可见持续强；MSCT定位准确率94%(47/50)，良恶性诊断准确率82%(41/50)。结论 MSCT多期扫描结合三维重建技术能准确显示腔外型胃肠道间质瘤的部位、形态、大小、密度及血供关系，对其良恶性判断具有一定临床价值。“,”Objective To investigate the imaging findings and diagnostic value of multi-slice spiral CT (MSCT) in the extraluminal gastrointestinal stromal tumor (GIST). Methods MSCT findings combined with three-dimensional (3D) reconstruction images of 50 patients with pathological y and surgical y proved extraluminal GIST were retrospectively analyzed. Al plain, dual-phase or Triple-phase contrast enhanced MSCT were performed preoperatively. Results The 50 cases of GIST, al extraluminal ,15 tumors were found in stomach, 15 in smal intestine (6 in duodenum, 6 in jejunum and 3 in ileum), 3 in sigmoid colon, 3 in rectum, 3 in omentum majus, 3 in mesentery, 5 in retroperitoneal, 4 in pelvic and 2 in bladder. 12 tumors were solid homogeneity mass. 38 were heterogeneous-solid tumors. 30 tumors were solid and necrosis. 24 were solid mass with hemor hage. 18 were complicated with hemor hage, necrosis or cystic degeneration. 3 were solid mass with calcification and 6 were pneumatosis. CT showed 40 cases with clear boundary, 19 cases of fate leaf and 3 cases of metastsis (including 4 cases of lymph node metastasis and 3 cases of recur ence). Tumor were mild to intense enhancement on contrast enhanced scan. Al lesions show marked enhancement at arterial phase were durative enhancement in venous and delayed phase.The accuracy for location and quality of MSCT were 94% (47/50) and 82%(41/50). Conclusion Multi-phase enhancement scan of MSCT and 3D-image reconstruction techniques have great value in diagnosing extraluminal gastrointestinal stromal tumors which can show the situation, shape, size, density and artery of the tumor clearly.