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目的:探讨克霉唑栓与氟康唑联合治疗老年念球菌性阴道炎的临床效果。方法:2012年1月至2012年12月选取110老年念球菌性阴道炎患者为研究对象,根据随机数字表将患者分为观察组及对照组各55例,对照组患者单纯应用氟康唑治疗,观察组在对照组基础上于睡前在阴道深处内置1枚克霉唑栓,持续治疗3周,对比分析两组患者治疗效果。结果:观察组总有效率高于对照组,而复发率低于对照组,差异有统计学意义(P<0.05),两组不良反应发生率无统计学意义(P>0.05)。结论:克霉唑栓与氟康唑联合治疗能有效提高患者治疗效果,降低患者术后复发率,安全有效。
Objective: To investigate the clinical effect of clotrimazole suppository combined with fluconazole in the treatment of elderly candidal vaginitis. Methods: From January 2012 to December 2012, 110 elderly patients with candidal vaginitis were selected as study subjects. According to the random number table, 55 patients were divided into observation group and control group, while those in control group were treated with fluconazole alone . The observation group was given one clotrimazole suppository in the vagina at bedtime on the basis of the control group, and the treatment group was treated for 3 weeks. The therapeutic effect was compared between the two groups. Results: The total effective rate in the observation group was higher than that in the control group, but the recurrence rate was lower than that in the control group (P <0.05). The incidence of adverse reactions in the two groups was not statistically significant (P> 0.05). Conclusion: The combination of clotrimazole suppository and fluconazole can effectively improve the therapeutic effect of patients and reduce the recurrence rate of patients, safe and effective.