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目的:对泼尼松联合来氟米特治疗狼疮性肾炎的临床效果进行分析。方法:资料随机选自2012年3月~2014年3月我院收治的狼疮性肾炎患者60例,将其平均分为两组,研究组和对照组,给予对照组患者环磷酰胺联合泼尼松治疗,研究组则采用泼尼松联合来氟米特治疗,并对两组临床资料进行回顾性分析。结果:经治疗后,研究组患者的总有效率以及临床观察指标均优于对照组,两组比较有差异具有统计学意义(P<0.05)。结论:给予狼疮性肾炎患者泼尼松联合来氟米特治疗的效果较为确切,值得在临床中推广和应用。
Objective: To analyze the clinical effect of prednisone and leflunomide in the treatment of lupus nephritis. Methods: The data were randomly selected from 60 patients with lupus nephritis who were admitted to our hospital from March 2012 to March 2014. The data were divided equally into two groups, the study group and the control group. Patients in the control group were treated with cyclophosphamide combined with prednisone Song treatment, the study group was treated with prednisone combined leflunomide, and the clinical data of two groups were retrospectively analyzed. Results: After treatment, the total effective rate of the study group and clinical observation indicators were better than the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion: The effect of prednisone combined with leflunomide given to patients with lupus nephritis is more exact and worthy of promotion and application in clinic.