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杀虫药剂作为外来化合物进入生物体后,常常会由于有机体的各种内部补偿性的防御机能,使这些化合物通过活化或解毒作用而排出体外,杀虫药剂在生物体内的代谢基本上可分为四种化学反应来完成,即氧化、水解、还原和合成。氧化、水解和还原是起始代谢,也是非合成代谢反应,杀虫药剂的解毒和活化作用基本上都在起始代谢过程中发生,因此非合成代谢是杀虫药剂代谢的最主要过程;合成反应乃是结合过程,是起始代谢产物及体内葡萄糖醛酸甙、甘氨酸和半胱氨酸等结合或合成为水溶性产物,最后排出体外。杀虫药剂在生物体
Insecticidal agents as foreign compounds into the organism, often due to various internal compensatory defensive function of the organism, so that these compounds through the activation or detoxification and excreted, insecticide metabolism in vivo can be basically divided into Four kinds of chemical reactions to complete, that is, oxidation, hydrolysis, reduction and synthesis. Oxidation, hydrolysis and reduction are the initial metabolic and non-anabolic reactions. The detoxification and activation of insecticides basically take place in the initial metabolic process. Therefore, non-synthetic metabolism is the most important process of insecticide metabolism. The reaction is the process of binding, is the initial metabolites and glucuronides in vivo, glycine and cysteine combination or synthesis of water-soluble products, and finally excreted. Insecticide in organisms