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良性前列腺增生症(BPH)是老年男性的一种常见病。α1阻滞剂能松弛平滑肌而使尿潴留症状得以缓解。另外,5α-还原酶抑制剂如非那雄胺(finasteride)等,具有抑制睾酮代谢的作用,从而能使前列腺的腺体变小。本研究探讨上述两类药合用时的药代动力学相互作
Benign prostatic hyperplasia (BPH) is a common disease in older men. α1 blockers can relax smooth muscle so that symptoms of urinary retention can be alleviated. In addition, 5α-reductase inhibitors such as finasteride and the like have the effect of inhibiting the metabolism of testosterone, thereby reducing the size of the prostate gland. This study explored the pharmacokinetic interaction of these two classes of drugs