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据《中华妇产科杂志》1995年30卷第12期报道 中国医学科学院肿瘤医院李爱苓等,对1958年2月~1987年10月该院子宫颈癌放射治疗后发生的放射性膀胱炎378例进行了回顾性分析。 结果表明,发生放射性膀胱炎的患者占同期行放射治疗子宫颈癌患者的3.2%。本病发生与年龄、放射治疗前临床分期、放射治疗方式(传统腔内治疗或后装腔内治疗)无明显关系,但与肿瘤生长类型及瘤体体积有关,本组66.5%的病例属外生型肿瘤。放射性膀胱炎的发病时间差异较大,但半数患者(51.1%)发病于放射治疗后2~5年,5~10年间发病者占16.7%,1年内发病者占3.4%。主要临床表现有:突发性血尿(占35.70%),顽固性血尿(占63.2%),膀胱阴道瘘(占1.1%)。目前尚无效果满意的治疗方法,5年生存率为90.4%,
According to the “Chinese Journal of Obstetrics and Gynecology” 1995 Volume 30 No. 12 Li Ailing Chinese Academy of Medical Oncology Cancer Hospital, from February 1958 to October 1987 the hospital after radiotherapy of cervical cancer occurred in 378 cases of radiation cystitis Retrospective analysis. The results showed that patients with radiation cystitis accounted for 3.2% of patients treated with radiotherapy for cervical cancer over the same period. The occurrence of this disease and age, before the clinical stage of radiation therapy, radiation therapy (traditional endovascular treatment or posterior endovascular treatment) no significant relationship, but with the type of tumor growth and tumor volume, the group of 66.5% of the cases are outside Genital tumor. The incidence of radiation cystitis varied widely, but half of the patients (51.1%) developed 2 to 5 years after radiotherapy. The incidence of these diseases was 16.7% in 5 to 10 years and 3.4% in 1 year. The main clinical manifestations are: hematuria (35.70%), refractory hematuria (63.2%), vesico-vaginal fistula (1.1%). At present there is no satisfactory treatment, 5-year survival rate was 90.4%