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目前虽已有几种分析前列腺素(PG)的先进化学方法,但生物检测法,由于简便易行,并可借以研究PG 类似物,且其专一性问题亦可通过被测样本的分离、提取和利用某些拮抗剂而大体解决,故仍被广泛采用。大鼠胃底条为常用的生物标本,因其灵敏度较佳,且对 PGE 及 F 系列均敏感(Davis H A et al:Brit J Pharmacol 46∶658,1972).然而此标本的稳定性似嫌不足,对制备的要求较高,如切取时伤及组织或灌液质地稍差(一般实验室所用水质及试剂质量常
At present, although there are several advanced chemical methods for the analysis of prostaglandin (PG), the bioassay method can be used to study PG analogues because of its simplicity and convenience, and its specificity can also be obtained through the separation of the tested samples, Extraction and use of certain antagonists and generally solve, it is still widely used. The rat gastric fundus is a commonly used biological sample because of its high sensitivity and sensitivity to both PGE and F series (Davis HA et al: Brit J Pharmacol 46: 658, 1972). However, the stability of this specimen seems inadequate , The preparation of the higher requirements, such as cut when injured tissue or poor texture slightly (general laboratory water quality and reagent quality often