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晚近,因广谱抗菌素滥用于治疗呼吸道感染而耐药肠道菌增多,又由于认识了肠杆菌可以传递耐药性的现象,因而对四环素、氨苄青霉素等广谱抗菌素用以治疗固紫阳性菌感染是否恰当提出怀疑。为观察狭谱抗菌素红霉素在细菌性上呼吸道感染中的疗效,作者在印度孟买某医院耳鼻喉门诊病例中选择体温在37℃以上急性扁桃体或咽部感染的成人患者111例,取咽含嗽液及喉拭培养,根据各种细菌培养结果按比例分成4个治疗组:无味红霉素(红霉素丙酸酯月桂基硫酸),红霉素硬脂酸盐,氨苄青霉素及土霉素组,疗程10天。治疗期间每日记录临床反应、副作用及进行细菌学培养。热退、症状体征消失为临床治愈。治疗10天仍有发热及症状则为临床失败,
Recently, due to the abuse of broad-spectrum antibiotics in the treatment of respiratory tract infections and increased resistance to enteric bacteria, but also because of the recognition of Enterobacteriaceae can transmit resistance phenomenon, which tetracycline, ampicillin and other broad-spectrum antibiotics used to cure solid-violet positive bacteria Infection is questionable. To observe the efficacy of the narrow-band antibiotic erythromycin in bacterial upper respiratory tract infection, the author selected 111 adult patients with acute tonsillar or pharyngeal infection whose body temperature was over 37 ℃ in the ENT clinic of a hospital in Mumbai, India, Liquid and laryngeal swab cultures were divided into 4 treatment groups according to the results of various bacterial cultures: Erythromycin (erythromycin propionate lauryl sulfate), erythromycin stearate, ampicillin and oxytetracycline Group, treatment for 10 days. Daily clinical records during treatment, side effects and bacterial culture. Retirement, symptoms and signs disappeared clinically cured. 10 days of treatment is still fever and symptoms are clinical failure,