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目的探讨有机磷农药中毒患者血清中C-反应蛋白(CRP)变化的临床意义。方法有机磷农药中毒患者20例,所有病例均于入院后次日早上空腹静脉采血3 ml,用日立7600型全自动生化分析仪胶乳凝集法测定CRP。并与22例门诊健康检查者对照。结果有机磷农药中毒患者血清中CRP水平较健康对照组明显增高(t=2.946,P<0.01);中毒越重,血清中CRP水平越高(t=2.725,P<0.01)。结论有机磷农药中毒患者血清中CRP的测定,对有机磷农药中毒患者的病情判定和疗效观察有重要临床意义。
Objective To investigate the clinical significance of serum C-reactive protein (CRP) in patients with organophosphorus pesticide poisoning. Methods Twenty patients with organophosphorus pesticide poisoning were enrolled in this study. All patients were admitted to the fasting venous blood 3 ml on the next morning after admission. CRP was determined by latex agglutination with Hitachi 7600 automatic biochemical analyzer. And with 22 cases of outpatient health check. Results Serum levels of CRP in organophosphorus pesticide poisoning patients were significantly higher than those in healthy controls (t = 2.946, P <0.01). The more severe the poisoning was, the higher CRP level was in serum (t = 2.725, P <0.01). Conclusion The determination of serum CRP in organophosphorus pesticide poisoning patients has important clinical significance in the judgment of the disease and the observation of curative effect in patients with organophosphorus pesticide poisoning.