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目的:探讨原发性高血压应用硝苯地平缓释片与氨氯地平治疗的效果,以丰富临床治疗经验。方法:选择我院接收的原发性高血压患者100例,根据入院治疗顺序随机分成对照组与观察组各50例,对照组采取服用硝苯地平缓释片治疗,观察组则给予氨氯地平片进行治疗,经治疗后,统计两组患者的血压情况、临床疗效及有关不良反应情况,将结果进行对比。结果:经治疗后,患者的临床症状均有明显的改善与缓解,观察组患者的治疗总有效率为92.00%,显著优于对照组的84.00%,比较差异显著(P<0.05);另外观察组患者的血压改善情况优于对照组,比较差异显著(P<0.05)。结论:原发性高血压应用氨氯地平片治疗疗效显著且不良反应少,相对于硝苯地平缓释片疗效更佳。
Objective: To investigate the effect of nifedipine sustained-release tablets and amlodipine in patients with essential hypertension to enrich clinical experience. Methods: A total of 100 patients with essential hypertension received in our hospital were randomly divided into control group (50 cases) and observation group (50 cases). The control group was given nifedipine sustained-release tablets while the observation group was given amlodipine Tablets for treatment, after treatment, statistics of two groups of patients with blood pressure, clinical efficacy and adverse reactions, the results were compared. Results: After treatment, the clinical symptoms were significantly improved and relieved. The total effective rate of the observation group was 92.00%, which was significantly better than that of the control group (84.00%) (P <0.05). In addition, The improvement of blood pressure was better in the patients than in the control group (P <0.05). Conclusion: The treatment of amlodipine in patients with essential hypertension has significant curative effect and few adverse reactions, which is better than that of nifedipine sustained-release tablets.