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环氧化酶 (Ｃｙｃｌｏｏｘｙｇｅｎａｓｅ ,ＣＯＸ)是前列腺素 (ＰＧｓ)合成过程中一个重要的限速酶 ,可将花生四烯酸 (ＡＡ)代谢成各种前列腺素产物 ,从而维持机体的各种生理病理过程。哺乳动物的环氧化酶至少有两种形式 :ＣＯＸ1和ＣＯＸ2 ,ＣＯＸ1结构性表达于大多数细胞内
Cyclooxygenase (COX) is an important rate-limiting enzyme in the synthesis of prostaglandin (PGs) and can metabolize arachidonic acid (AA) into a variety of prostaglandin products to maintain the body’s various physiological pathologies process. Mammalian cyclooxygenases have at least two forms: COX1 and COX2, which are constitutively expressed in most cells