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目的:为监测头孢拉定的药物不良反应.方法:通过静脉注射头孢拉定致血尿6例;系统进行检索,并筛选和分析后,综合头孢拉定致血尿的中文文献资料.结果:在检索的15篇报道中,共发现静脉注射头孢拉定致血尿47例,一般表现为肉眼血尿,只有少数患者伴有腹痛、尿路刺激征或颜面水肿.47例患者肾功能均正常,病程短,停药后预后良好.结论:从本组病例报告和从文献分析角度来看,静脉注射头孢拉定可引起一过性肾损害.
Objective: To monitor the adverse drug reactions of cefradine.METHODS: 6 cases of hematuria caused by cefradine were injected intravenously and were systematically searched, screened and analyzed, and then the Chinese literatures about the result of cefradine were given.Results: Of the 15 reported articles, A total of 47 cases of hematuria caused by intravenous cephradine were found, with gross hematuria, only a few patients were accompanied by abdominal pain, urinary tract irritation or facial edema.47 patients had normal renal function, short course of disease and good prognosis after stopping drug.Conclusion: From this group of case reports and from the literature analysis point of view, intravenous cefradine can cause transient renal damage.