三磷酸腺苷与骨髓间充质干细胞联合移植对损伤脊髓中神经元特异性烯醇化酶表达的影响

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目的探讨三磷酸腺苷(ATP)与骨髓间充质干细胞(BMSCs)复合物联合移植对损伤脊髓的修复及脊髓中神经元特异性烯醇化酶(NSE)表达的影响。方法将48只SD雌性大鼠采用改良Allen’s打击法制备T<sub>12</sub>节段脊髓损伤模型后,随机分为4组,12只/组,A组(ATP+BMSCs联合移植组)、B组(BMSCs移植组)、C组(ATP移植组)、D组(空白对照组)。术后采用Rivlin斜板实验评价后肢功能恢复程度,于28 d处死大鼠后取材行组织学和免疫组织化学染色,观察NS
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