论文部分内容阅读
目的评估比阿培南治疗铜绿假单胞菌(PAE)下呼吸道感染临床疗效和安全性。方法 88例下呼吸道PAE感染患者随机分为治疗组与对照组,分别使用比阿培南和亚胺培南/西司他丁治疗,疗程均为10～14d。结果治疗组总有效率为88.6%,细菌清除率为90.9%,均高于对照组的70.5%、75.0%,两组不良反应发生率较低。结论比阿培南治疗PAE下呼吸道感染临床疗效可靠且安全。
Objective To evaluate the clinical efficacy and safety of biapenem in treating lower respiratory tract infection of Pseudomonas aeruginosa (PAE). Methods Eighty-eight patients with lower respiratory tract PAE infection were randomly divided into treatment group and control group. The patients were treated with biapenem and imipenem / cilastatin respectively for 10-14 days. Results The total effective rate was 88.6% and the bacterial clearance rate was 90.9% in the treatment group, which were both higher than 70.5% and 75.0% of the control group, with a lower incidence of adverse reactions in both groups. Conclusion Biapenem has a reliable and safe therapeutic effect on PAE lower respiratory tract infection.