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本文检测了４４例老年冠心病（ＣＨＤ）患者血清脂质丙二醛（ＭＤＡ）和超氧化物歧化酶（ＳＯＤ）的含量，并与健康老年人对照比较，同时对心绞痛发作期与缓解病人比较分析，结果显示，除胆固醇外其余各项指标两组间均有显著差异（Ｐ＜０．０５）。多元回归分析表明，血清低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）与ＭＤＡ呈显著正相关（Ｐ＜０．００１），血清高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）与ＳＯＤ亦是显著正相关（Ｐ＜０．００１）。提示高脂血症与脂质过氧化、ＳＯＤ降低与ＭＤＡ 增高和ＣＨＤ慢性心肌缺血有一定关系。它对判断老年ＣＨＤ病情及预后有重要参考意义。
In this study, serum lipid levels of malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in 44 cases of elderly patients with coronary heart disease (CHD) and compared with healthy controls, meanwhile, the patients with angina pectoris and remission were compared Analysis, the results showed that, in addition to cholesterol, the rest of the indicators were significantly different between the two groups (P <0.05). Multiple regression analysis showed that there was a significant positive correlation between serum LDL-C and MDA (P <0.001), serum HDL-C and SOD (P <0.001). Tip hyperlipidemia and lipid peroxidation, decreased SOD and increased MDA and chronic myocardial ischemia have a certain relationship. It has an important reference value for judging the condition and prognosis of elderly CHD.