论文部分内容阅读
目的探讨新生儿窒息后血清超敏C-反应蛋白(hs-CRP)和心肌酶谱水平变化及与窒息程度的关系。方法利用全自动生化分析仪对42例窒息新生儿与20例无窒息新生儿血清hs-CRP、血清谷草转氨酶(AST)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)进行对照检测。结果新生儿窒息组血清hs-CRP和心肌酶谱水平明显增高(P均<0.01),且重度窒息组高于轻度窒息组(P均<0.01)。结论 hs-CRP和心肌酶谱定量测定可作为新生儿窒息后心肌损害的早期、灵敏、特异的诊断指标。
Objective To investigate the changes of serum hs-CRP and myocardial zymogram after asphyxia and the relationship with asphyxia. Methods The serum hs-CRP, serum aspartate aminotransferase (AST), lactate dehydrogenase (LDH), creatine kinase (CK) and creatine kinase (CK) in 42 neonates with asphyxia and 20 neonates without asphyxia were detected by automatic biochemical analyzer Isoenzyme (CK-MB) for control testing. Results Serum levels of hs-CRP and myocardial enzymes were significantly increased in neonatal asphyxia group (all P <0.01), and those in severe asphyxia group were higher than those in mild asphyxia group (all P <0.01). Conclusion The quantitative determination of hs-CRP and myocardial enzymes can be used as an early, sensitive and specific diagnostic indicator of myocardial damage after neonatal asphyxia.