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许多糖尿病患者对胰岛素治疗存在顾虑,担心注射带来不适、害怕发生低血糖以及体重增加,这给获得最佳血糖控制带来了挑战。基础胰岛素治疗对T2DM患者来说是一种有效且安全的方式。随着患者胰岛β细胞功能的进行性衰退,基础联合餐时速效胰岛素治疗成为了生理性胰岛素替代治疗的金标准方案。与中性鱼精蛋白锌胰岛素(NPH)相比,地特胰岛素(DET)治疗对体重增加影响较小和低血糖发生
Many diabetic patients have concerns about insulin therapy, worry about the discomfort caused by injection, fear of hypoglycemia and weight gain, which poses a challenge to get the best blood glucose control. Basal insulin therapy is an effective and safe way for T2DM patients. With the progressive decline of pancreatic beta-cell function in patients, basal combined with fasting insulin therapy has become the gold standard for physiologic insulin replacement therapy. Dextrose (DET) treatment has less effect on weight gain and hypoglycemia than neutral protamine zinc insulin (NPH)