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目的:观察康艾注射液联合卡铂胸腔注射治疗恶性胸腔积液的临床疗效及不良反应。方法:将48例恶性胸腔积液的患者随机分成对照组、观察组:对照组单用卡铂注入胸腔,观察组用康艾注射液联合卡铂分别注入胸腔,比较两组间疾病治疗有效率及不良反应。结果:对照组和观察组有效率(CR+PR)分别为65.2%和84.0%,两组间差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,两组间差异有统计学意义(P<0.05)。结论:康艾注射液联合卡铂胸腔注射治疗恶性胸水,可提高疗效,减轻不良反应。
Objective: To observe the clinical efficacy and adverse reactions of Kangai injection combined with carboplatin in the treatment of malignant pleural effusion. Methods: 48 patients with malignant pleural effusion were randomly divided into control group, observation group: the control group was injected with carboplatin alone, the observation group with Kang Ai injection combined with carboplatin were injected into the chest cavity, the effective rate of treatment between the two groups And adverse reactions. Results: The effective rates (CR + PR) of the control group and the observation group were 65.2% and 84.0%, respectively, with significant difference between the two groups (P <0.05). The incidence of adverse reactions in the observation group was lower than that in the control group, with significant difference between the two groups (P <0.05). Conclusion: Kangai injection combined with carboplatin in the treatment of malignant pleural effusion can improve curative effect and reduce adverse reactions.