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目的了解深圳市南山区2013—2014年细菌性感染性腹泻致病菌的病原构成、流行特征及主要致病菌的血清型分布。方法依托深圳市建立的腹泻监测网络,本辖区哨点医院采集门诊未使用抗生素腹泻监测病例的大便样本、肛拭子或呕吐物标本,进行致病菌的分离培养,疾病预防控制中心对阳性菌株进行复核和分析。结果在582份标本中,共分离到47株菌,检出率为8.1%。其中沙门菌位居阳性检出菌的首位,占51.1%(24/47),肠致泻性大肠杆菌、空肠弯曲菌、副溶血性弧菌分别占31.9%(15/47)、10.6%(5/47)、6.4%(3/47),不同性别、年龄段和时间患者病原菌感染情况差异无统计学意义(P>0.05)。结论南山区细菌性感染性腹泻主要致病菌依次为沙门菌、肠致泻性大肠杆菌、空肠弯曲菌、副溶血性弧菌,沙门菌在人群和时间的分布具有广泛性。
Objective To understand the pathogenic constitution, epidemiological characteristics and serotype distribution of the main pathogenic bacteria of bacterial infectious diarrhea pathogens from 2013 to 2014 in Nanshan District, Shenzhen. Methods Based on the diarrhea monitoring network established in Shenzhen City, the sentinel hospitals in this area collected the stool samples, the samples of anal swabs or vomit that were not used in the outpatient monitoring of antibiotic diarrhea, and isolated and cultured pathogenic bacteria. The Center for Disease Control and Prevention Review and analyze. Results Among 582 samples, 47 strains were isolated and the detection rate was 8.1%. Among them, Salmonella belonged to the first place with positive detection, accounting for 51.1% (24/47), intestinal digesting Escherichia coli, Campylobacter jejuni and Vibrio parahaemolyticus accounting for 31.9% (15/47) and 10.6% 5/47), 6.4% (3/47). There was no significant difference in pathogen infection among different sexes, age groups and time (P> 0.05). Conclusion The main pathogens of bacterial infectious diarrhea in Nanshan District are salmonella, enterohemorrhagic Escherichia coli, Campylobacter jejuni, Vibrio parahaemolyticus and Salmonella in population and time.