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目的探讨口服优思明促进人工流产(人流)术后子宫内膜增长及月经转归的效果。方法择期行人流术患者408例,随机分为用药组和对照组各204例。对照组人流术后常规服用抗生素预防感染;用药组于手术当日除服用抗生素预防感染外,同时加服优思明(每片含炔雌醇0.03mg和屈螺酮3mg),每日一片,连续服用21d为1个周期,共用3个周期停药,间隙期7d。比较两组患者术后出血量、阴道流血持续时间和术后第21天子宫内膜厚度。结果用药组阴道出血少于经量的患者比例明显大于对照组(62.7%vs.47.5%)(P<0.05);用药组阴道流血持续时间亦短于对照组[(5.0±2.6)d vs.(7.0±2.1)d)](P<0.05)。用药组术后第3周子宫内膜厚度大于对照组[(6.2±2.0)mm vs.(5.0±1.8)mm](P<0.05)。结论人流后患者服用优思明,对减少术后出血量、缩短阴道流血时间、促进子宫内膜增长及月经转归有明显效果。
Objective To investigate the effects of oral Yuesi Ming to promote endometrial growth and menstrual outcome after induced abortion (abortion). Methods A total of 408 patients undergoing elective pedestrian ablation were randomly divided into treatment group (n = 204) and control group (n = 204). In the control group, routine antibiotics were used to prevent infection after abortion. In addition to taking antibiotics to prevent infection, the medication group was given Yasmin (0.03 mg of ethinyl estradiol and 3 mg of drospirenone) on the day of surgery, one tablet per day Take 21d for a cycle, sharing three cycles of drug withdrawal, the gap of 7d. The amount of postoperative bleeding, the duration of vaginal bleeding and the thickness of endometrium on the 21st postoperative day were compared between the two groups. Results The proportion of vaginal bleeding in the medication group was significantly higher than that in the control group (62.7% vs 47.5%, P <0.05). The duration of vaginal bleeding in the medication group was also shorter than that in the control group (5.0 ± 2.6 d vs. (7.0 ± 2.1) d)] (P <0.05). The thickness of endometrium in the third week after operation in the medication group was significantly larger than that in the control group [(6.2 ± 2.0) mm vs. (5.0 ± 1.8) mm] (P <0.05). Conclusions After abortion, patients taking Yasmin can reduce the amount of postoperative bleeding, shorten the time of vaginal bleeding, and promote the growth of endometrium and the outcome of menstruation.