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目的 寻找重症急性胰腺炎(severe acute pancreatitis,SAP)早期液体复苏与腹腔间隙综合征的关系,为临床治疗提供合理方法.方法 统计本科2011年1月-2015年12月符合重症急性胰腺炎诊断标准的135例住院患者,其中男79例,女56例.根据入院后扩容达标时间分为快速扩容组(a组,自入院24 h内快速扩容,48例)、控制扩容组(b组,自入院24～72 h内控制扩容,87例),按照快速液体复苏和控制性液体复苏的方案给予治疗.观察两组入院当日至入院后72 h内液体潴留总量,腹腔间隙综合症发生率.结果 液体潴留总量b组显著低于a组(P＜0.05);腹腔间隙综合征发生率a组显著高于b组(P＜0.05).结论 控制性液体复苏不仅可以达到复苏目的,又可以明显降低腹腔间隙综合征的发生率,适用于重症急性胰腺炎的早期液体复苏.“,”Objective To explore the relationship between early fluid resuscitation and abdominal compartment syndrome (SAP) in severe acute pancreatitis (SAP), and to provide a appropriate method for clinical treatment.the study was begun.Methods 135 inpatients of severe acute pancreatitis admitted to our department from Jan.2011 to Dec.2015 were recruited in this study, including 79 males and 56 females.The cases group(Group A, 48 patients with quick liquid expansion within 24 hours after admission).control expansion group (group b, 87 patients with controlled liquid expansion within 24 t0 72 hours after admission), according to the rapid liquid resuscitation and controlled fluid resuscitation references.The amount of fluid retention and incidence of abdominal compartment syndrome within 72 hours after admission were analyzed.Results The total fluid retention in group b was significantly lower than that in group a (P ＜0.05).The incidence of abdominal compartment syndrome was significantly higher in group a than b (P ＜0.05).Conclusion Controlled fluid resuscitation can not only help to achieve the purpose of resuscitation, but also significantly reduce the incidence of abdominal compartment syndrome, is preferred to early fluid resuscitation of SAP.