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H~+/K~+-ATP酶作为离子泵在胃酸从壁细胞分泌的终末过程中担负着把H~+与K~+交换向胃腔内主动转运的任务。奥美拉唑(Omeprazole)作为特异的H~+/K~+-ATP酶阻断药,对胃酸分泌的抑制作用比H_2受体阻断剂更强。作者就奥美拉唑对胰岛素刺激分泌的效果进行了探讨。对象为健康人7例、十二指肠溃疡者2例共9例。口服本品20mg一日1次。同一受试者进行2次胃液采取试验。第一次为对照组试验,即仅进行胰岛素刺激试验;第二
As an ion pump, H ~ + / K ~ + -ATPase plays an important role in the active transport of H ~ + and K ~ + into gastric cavity during the process of gastric acid secretion from parietal cells. Omeprazole, as a specific H ~ + / K ~ + -ATPase inhibitor, has a more potent inhibitory effect on gastric acid secretion than H 2 receptor blockers. The authors discussed the effect of omeprazole on insulin secretion. 7 cases of healthy subjects, 2 cases of duodenal ulcer in a total of 9 cases. Oral 20mg a day. The same subject to take 2 gastric juice to take the test. The first for the control group test, that is, only insulin stimulation test; second