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目的:探讨氨氯地平联合他汀类药物治疗高血脂症合并高血压的临床疗效。方法:对我院2014年8月至2016年8月456例血脂症合并高血压患者的临床资料进行回顾性分析,将所有患者根据随机抽签原则分为对照组228例和研究组228例,对照组患者单用氨氯地平治疗,研究组患者在对照组的基础上联合应用阿托伐他汀钙治疗,对比两组患者的临床疗效及治疗后各指标变化。结果:研究组显效149例,有效63例,无效16例,治疗总有效率92.98%,对照组显效100例,有效77例,无效51例,治疗总有效率77.63%,两组比较差异有统计学意义(P<0.05),治疗后研究组患者的血压、血脂水平均明显改善,与对照组比较,研究组改善程度更为显著,两组比较差异有统计学意义(P<0.05)。结论:对高血脂症合并高血压患者联合应用氨氯地平与他汀类药物能有效改善患者的血脂、血压水平,疗效显著,具有重要的临床应用价值。
Objective: To investigate the clinical efficacy of amlodipine plus statins in the treatment of hyperlipidemia complicated with hypertension. Methods: A retrospective analysis was performed on the clinical data of 456 cases of patients with hyperlipidemia in our hospital from August 2014 to August 2016. All patients were divided into control group (228 cases) and study group (228 cases) Patients in group A were treated with amlodipine alone. Patients in study group were treated with atorvastatin calcium on the basis of the control group, and the clinical efficacy and the changes after treatment were compared between the two groups. Results: The study group markedly effective in 149 cases, effective 63 cases, 16 cases ineffective, the total effective rate was 92.98%, the control group markedly effective 100 cases, effective 77 cases, ineffective in 51 cases, the total effective rate was 77.63%, the difference between the two groups statistics (P <0.05). After treatment, the blood pressure and blood lipid level of the study group were significantly improved. Compared with the control group, the improvement degree of the study group was more significant, the difference was statistically significant (P <0.05). Conclusion: The combination of amlodipine and statin can effectively improve the level of blood lipids and blood pressure in hyperlipidemic patients with hypertension, and has a significant curative effect. It has important clinical value.