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目的:统计分析抗高血压药临床应用情况,为合理选择抗高血压药提供依据。方法:采用金额排序法和用药频次(DDDs)排序法,对我门诊部2006-2008年抗高血压药使用情况进行统计分析,得出各年度用药金额和DDDs靠前的抗高血压药。结果:用药类别排在前6位的药物为钙拮抗药(CCB)、β受体阻断药、血管紧张素转换酶抑制药(ACEI)、血管紧张素Ⅱ受体拮抗药(ARB)、利尿药和α受体阻断药;用药金额排在前10位的品种为左旋氨氯地平片、硝苯地平缓释片Ⅱ、氨氯地平片、硝苯地平控释片、美托洛尔片、福辛普利钠法等;DDDs排在前10位的品种为左旋氨氯地平片、硝苯地平缓释片Ⅱ、硝苯地平缓释片Ⅰ、美托洛尔片、苯磺酸氨氯地平片、硝苯地平控释法等。结论:CCB为我门诊部抗高血压用药最多的品种,新型抗高血压药ARB为增长迅速的品种。
Objective: To analyze the clinical application of antihypertensive drugs statistically and provide the basis for the rational choice of antihypertensive drugs. Methods: We analyzed the use of antihypertensives in our clinics from 2006 to 2008 by the method of order of magnitude and DDDs, and obtained the antihypertensives with the annual amount of medication and DDDs. Results: The drugs with the top six drug categories were calcium antagonist (CCB), beta blocker, angiotensin converting enzyme inhibitor (ACEI), angiotensin Ⅱ receptor antagonist (ARB), diuretic Drugs and α-receptor blockers; the top 10 drugs in terms of dosage were levamlodipine tablets, nifedipine sustained-release tablets Ⅱ, amlodipine tablets, nifedipine controlled release tablets, metoprolol tablets , Fosinopril sodium method, etc .; DDDs ranked the top 10 varieties of levamlodipine tablets, nifedipine sustained release tablets Ⅱ, nifedipine sustained release tablets Ⅰ, metoprolol tablets, ammonia benzene sulfonate Chlorpheniramine tablets, nifedipine controlled release method. Conclusion: CCB is the most used antihypertensive drug in my clinic, and ARB, a new type of antihypertensive drug, is a rapidly growing variety.