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分别对幼年、成年及老年大鼠耳蜗核的体积、神经元的核仁体积和耳蜗核神经元的数量进行检测。结果示：老年大鼠耳蜗核体积与成年组相差无显著性意义（P＞0．05）；神经元核仁体积，老年组较其它两组有极显著性缩小（P＜0．01）；老年组球形细胞和多极细胞均明显减少（P＜0．01）；梭形细胞与其它两组相差无显著意义，而胶质细胞极明显增多，平均增多48．5％（P＜0．01）。表明老年性聋的病理变化不仅发生在耳蜗，而区发生在蜗神经核。认识了这一点，对于进一步理解老年性聋的发病机理，指导临床工作具有重要意义。
The volume of cochlear nucleus, the nucleolus of neurons and the number of cochlear neurons in juvenile, adult and aged rats were detected respectively. The results showed that there was no significant difference in the cochlear nuclear volume between the aged rats and the adult rats (P> 0.05). The nucleolar volume of the neurons in the aged rats was significantly reduced compared with the other two groups (P <0.01). Spherical cells and multipolar cells were significantly decreased in the elderly group (P <0.01). Spindle cells were not significantly different from the other two groups, while glial cells were significantly increased, with an average increase of 48.5% (P <0. 01). The pathological changes of senile deafness not only occur in the cochlea but in the cochlear nucleus. Understanding this point is of great significance for further understanding the pathogenesis of senile deafness and guiding clinical work.