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目的：探讨婴儿肺炎并发多器官衰竭的早期预防。方法：将１６０例无器官衰竭又无其它合并症及并发症的病情较重的患儿随机分为预防组和对照组各８０例，对照组予以常规治疗，预防组则在常规治疗基础上同时予以川芎嗪注射液、酚妥拉明、毒毛旋花子甙Ｋ治疗。结果：预防组各器官衰竭发生率明显下降，其中发生心力衰竭１４例次；氧分压（ＰａＯ２）升高７０例，降低１０例；二氧化碳分压（ＰａＣＯ２）下降６８例，升高１２例；死亡３例（３．７５％）；对照组各器官衰竭发生率明显升高（２组比较Ｐ＜０．０５和Ｐ＜０．０１），其中发生心力衰竭３６例次；ＰａＯ２升高５６例，下降２４例；ＰａＣＯ２下降５２例，升高２８例；死亡１１例（１３．７５％）。结论：对较重的婴儿肺炎早期采取预防措施可改善缺氧和二氧化碳潴留，降低多器官衰竭的发生率和病死率。
Objective: To explore the early prevention of infant pneumonia complicated by multiple organ failure. Methods: 160 cases without organ failure and no other complications and complications in children with severe disease were randomly divided into preventive group and control group of 80 cases, the control group to be routine treatment, prevention group is based on conventional treatment at the same time To be tetramethylpyrazine injection, phentolamine, poisonous hair spinosad K treatment. Results: The incidence of organ failure in prevention group decreased significantly, of which heart failure occurred in 14 cases; PaO2 increased in 70 cases and decreased in 10 cases; PaCO2 decreased in 68 cases and increased in 12 cases; (3.75%) died in the control group. The incidence of organ failure in the control group was significantly higher (P <0.05 and P <0.01 for both groups), with 36 cases of heart failure and 56 cases of PaO2 , Down 24 cases; PaCO2 decreased 52 cases, an increase of 28 cases; 11 cases died (13.75%). Conclusions: Early prophylaxis of heavier infant pneumonia can improve hypoxia and carbon dioxide retention, and reduce the incidence and mortality of multiple organ failure.