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我科于1997年4月～10月用东菱精纯克栓酶(DF-521)治疗脑梗死50例,现报告如下: 1 资料与方法 1.1 一般资料 50例均为住院患者,男28例,女22例,年龄36岁～72岁,平均年龄54岁,其中腔隙性脑梗死20例,颈内动脉系统TIA5例,大脑中动脉系统梗塞15例,脑干梗死4例,大面积脑梗死6例,所有病例均做头颅CT或头颅MRI证实,并排除其它出血性疾病的可能,50例患者用药前均查血小板,出凝血时间为正常范围。 1.2 病史及体征 既往有高血压病史28例,糖尿病史10例,高心病或冠心病房颤患者9例,有2次～3次脑梗死5例,发病后的主要体征为昏迷、失语、语言障碍、偏瘫等。 1.3 诊断标准 按1986年全国脑血管病学术会议
Our department in April 1997 to October with Diltiazem Keke enzyme (DF-521) treatment of cerebral infarction in 50 cases, are as follows: 1 Materials and Methods 1.1 General Information 50 patients were hospitalized, 28 males , 22 females, aged 36 years old to 72 years old, mean age 54 years old, including lacunar infarction in 20 cases, internal carotid artery TIA5 cases, 15 cases of middle cerebral artery occlusion, brainstem infarction in 4 cases, large brain Infarction in 6 cases, all cases were craniocerebral CT or craniocerebral MRI confirmed, and exclude the possibility of other bleeding disorders, 50 patients were examined before administration of platelets, clotting time for the normal range. 1.2 history and signs of previous history of hypertension in 28 cases, 10 cases of diabetes history, high heart disease or coronary heart disease in 9 patients with atrial fibrillation, there are 2 to 3 cerebral infarction in 5 cases, the main signs of post-onset coma, aphasia, language Obstacles, hemiplegia and so on. 1.3 diagnostic criteria by 1986 National Conference on cerebrovascular disease