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目的:报告1例男性患者合并有匹克威克综合征和阻塞性睡眠呼吸暂停(OSA),其临床表现为假性脑瘤和视力下降。方法:病例报告。结果:患者,男,54岁,过度肥胖,诉双眼视力渐降3mo,检查示:视力:右眼20/200,左眼20/400,左眼合并色觉异常,眼底镜示双视乳头水肿和视盘旁出血,左眼合并黄斑部渗出。体格检查和实验室检查符合阻塞性睡眠呼吸暂停与匹克威克综合征诊断。腰椎穿刺:开放压350mmHg,脑部扫描正常。诊断:OSA和匹克威克综合征相关性假性脑瘤。眼底表现和视力随采血治疗、血压控制、体重控制及双层正压通气治疗而改善。结论:对于患有假性脑瘤的患者,必须对阻塞性睡眠呼吸暂停与匹克威克综合征有所警惕。
PURPOSE: To report 1 male patient with Pickwick syndrome and obstructive sleep apnea (OSA) whose clinical manifestations are pseudo-brain tumors and decreased vision. Methods: Case report. Results: The patient, male, 54 years old, overweight, vomiting binocular vision decreased 3mo, examination showed: visual acuity: right eye 20/200, left eye 20/400, left eye with color vision abnormalities, fundus binocular nipple edema and Disc near the bleeding, the left eye with macular exudation. Physical examination and laboratory tests are consistent with obstructive sleep apnea and Pickwickian syndrome. Lumbar puncture: open pressure 350mmHg, brain scan is normal. Diagnosis: OSA and Pickwickian syndrome-associated pseudo-brain tumors. Fundus performance and visual acuity with blood treatment, blood pressure control, weight control and double positive pressure ventilation to improve. Conclusion: In patients with pseudo-brain tumors, obstructive sleep apnea and Pickwickian syndrome must be observed.