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目的探讨血浆脑钠肽(BNP)水平对老年心力衰竭的诊断价值。方法收集96例资料完整的老年心衰患者以及30例健康对照者的临床资料,观察不同心功能分级的心衰患者血浆BNP水平以及与超声心动图相关指标的关系。结果老年心力衰竭患者的BNP水平明显高于健康对照组,血浆BNP水平与左室射血分数呈负相关(r=-0.67,P<0.01),与左室舒张末期内径呈正相关(r=0.62,P<0.01)。结论对老年心衰患者BNP测定是诊断心力衰竭的可靠指标。
Objective To investigate the diagnostic value of plasma brain natriuretic peptide (BNP) in senile heart failure. Methods The clinical data of 96 elderly patients with heart failure and 30 healthy controls were collected to observe the relationship between plasma BNP levels and echocardiographic parameters in patients with different heart function classifications. Results BNP levels in elderly patients with heart failure were significantly higher than those in healthy controls. Plasma BNP level was negatively correlated with left ventricular ejection fraction (r = -0.67, P <0.01), and positively correlated with left ventricular end diastolic diameter (r = 0.62 , P <0.01). Conclusion BNP in elderly patients with heart failure is a reliable indicator of heart failure diagnosis.