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本研究对口腔鳞状细胞癌(SCC)患者观察临床各分期(TNM)及手术前后T细胞亚群变化,测定SCC患者手术前后外周血中NK细胞活性动态变化,报道如下。 材料和方法 一、临床资料 15例口腔SCC患者均经活检证实,未经任何治疗。其中男13例,女2例。最大年龄64岁,最小32岁,平均51岁。病灶部位:牙龈6例,舌3例,颊3例,腭1例,唇2例。按照WHO口腔鳞状细胞癌分级标准,肿瘤临床分期(TNM);Ⅰ期2例,Ⅱ期4例,Ⅲ期6例,Ⅳ期3例。15例正常对照为健康献血员,男10例,女5例,年龄30～50岁。
This study of oral squamous cell carcinoma (SCC) in patients with clinical stages (TNM) and T cell subsets before and after surgery to determine changes in peripheral blood of SCC patients before and after surgery NK cell activity dynamic changes reported as follows. Materials and Methods First, clinical data 15 cases of oral SCC patients were confirmed by biopsy, without any treatment. There were 13 males and 2 females. The oldest is 64 years old, the youngest is 32 years old and the average is 51 years old. Lesions: 6 cases of gums, 3 cases of tongue, 3 cases of cheek, 1 case of palate, 2 cases of lip. According to the WHO classification criteria of oral squamous cell carcinoma, the clinical stage (TNM) of tumor was 2 cases in stage Ⅰ, 4 cases in stage Ⅱ, 6 cases in stage Ⅲ and 3 cases in stage Ⅳ. Fifteen normal controls were healthy blood donors, 10 males and 5 females, aged 30 to 50 years old.