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从LaDue氏等首次报告肝病患者血清中谷氨酸—草酰乙酸转氨酶活力增高已经二十年了。这期间有关转氨酶在各种疾病中变化的情况报道得很多。就肝炎而论,转氨酶活力测定对早期诊断、疗效观察、预后估计以及流行病学调查等方面都提供了有价值的线索,但有时也可能引起一些模糊的概念。因此复习转氨酶的临床生物化学,以便正确评价和使用它,在当前防治肝炎工作中是有实际意义的。
It has been twenty years since LaDue et al. First reported an increase in glutamate oxaloacetate aminotransferase serum from patients with liver disease. During this period, many reports on the changes of aminotransferases in various diseases have been reported. In the case of hepatitis, the determination of transaminase activity provides valuable clues to early diagnosis, efficacy observation, prognosis estimation and epidemiological investigation, but it may sometimes cause some vague concept. Therefore reviewing the clinical biochemistry of aminotransferases in order to properly evaluate and use it is of practical significance in the current work on the prevention and treatment of hepatitis.