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目的：观察受精卵着床前给黄体酮治疗是否可以提高黄体功能不全者孕酮值以及对其妊娠结局的影响。方法：收集2013年1月-2014年6月期间我院门诊以及住院的习惯性流产患者共42例（其中治疗组17例，对照组25例），两组都进行抽取静脉血来检测血清孕酮值。对两组初次检测的孕酮值进行比较，并跟踪观察来确定用本法治疗后对患者的妊娠结局是否有影响。结果：治疗组首次所测得的孕酮值明显高于对照组，差别有统计学意义（P<0.05）。并且根据跟踪统计患者妊娠率的数据显示，治疗组疗效明显高于对照组。结论：提前给药可以提高黄体功能不全者的孕酮值进而提高她们的临床妊娠率。“,”Objective To observe the effects of progesterone therapy to the patients with corpus luteum insufficiency before implantation and their pregnancy outcomes. Methods From January 1992 to June 1994, a total of 42 recurrent spontaneous abortion women were col ected from outpatient and inpatient, and randomly divided into treatment group ( 17 cases) and control group (25 cases). Venous blood from the two groups was col ected to determine the value of serum progesterone, and comparison was made between the two groups, and the effects of progesterone therapy were observed fol owing up. Results The preliminary value of serum progesterone and rate of pregnancy was significantly higher in treatment group than that in control group (P<0.05).Conclusion Progesterone therapy could improve clinical pregnancy rate of patients with corpus luteum insufficiency by increase serum progesterone level.