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目的观察新辅助动脉灌注化疗栓塞联合经尿道等离子切除术治疗浸润性膀胱癌的疗效。方法 48例不能接受膀胱全切术的浸润性膀胱癌患者,按治疗方法不同分为对照组(20例)和观察组(28例)。对照组单纯行经尿道等离子切除术,观察组行新辅助动脉灌注化疗栓塞联合经尿道等离子切除术,对比观察两组疗效与不良反应发生情况。结果观察组总有效率高于对照组(P<0.05),两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论对于不能接受膀胱全切术的患者,新辅助动脉灌注化疗栓塞联合经尿道等离子切除术治疗浸润性膀胱癌疗效显著,复发率低,值得推广。
Objective To observe the effect of neoadjuvant arterial infusion chemotherapy combined with transurethral resection of the bladder in the treatment of invasive bladder cancer. Methods Forty-eight patients with invasive bladder cancer who failed to undergo total bladder resection were divided into control group (n = 20) and observation group (n = 28) according to the different treatment methods. The control group was treated with transurethral plasmapheresis alone. The observation group received neoadjuvant arterial chemoembolization combined with transurethral resection of plasma to observe the curative effect and adverse reactions of the two groups. Results The total effective rate in the observation group was higher than that in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion For those patients who can not undergo complete mastectomy, neoadjuvant arterial infusion of chemoembolization and transurethral resection of the bladder for the treatment of invasive bladder cancer have a significant effect and low recurrence rate, which deserves promotion.