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自发性腹膜炎(SBP)是肝硬化最常见的并发症之一,SBP是指无腹腔脏器穿孔、炎症(如脓肿、急性胰腺炎、胆囊炎)等感染原因而发生的腹膜急性弥漫性细菌性感染。最近一项为期2a的大规模前瞻性研究显示,SBP是肝硬化患者入院时或住院期间最常见的细菌感染,感染率达24%(138/527)〔1〕。首次SBP后幸存者的1a和2a生存率分别为30%~50%和25%~30%〔2〕。为获得早期诊断的依据,笔者对天津市传染病医院近3a来收治的140例肝硬化合并SBP患者住院病例进行回顾性分析。
Spontaneous peritonitis (SBP) is one of the most common complications of cirrhosis. SBP refers to the peritoneal acute diffuse bacterial that occurs without perforation of abdominal organs and inflammation (such as abscess, acute pancreatitis, cholecystitis) infection. A recent large prospective study of 2a showed that SBP was the most common bacterial infection on admission to hospital or during hospitalization, with a prevalence of 24% (138/527) [1]. Survival rates of survivors 1a and 2a after initial SBP were 30% -50% and 25% -30%, respectively (2). In order to obtain the basis of early diagnosis, the author retrospectively analyzed 140 inpatients with cirrhosis and SBP who had been treated in Tianjin Infectious Diseases Hospital for nearly 3 years.