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目的：探讨氯化汞（ＨｇＣｌ２）对小鼠毒性作用。方法：采用毒理学方法观察ＨｇＣｌ２对小鼠体重、脏器系数和精子畸形率的影响，并作Ｆ检验和ｑ检验以及ｕ检验。结果：ＨｇＣｌ２２．０ｍｇ／ｋｇ和１．０ｍｇ／ｋｇ体重染毒后体重增长明显低于阴性对照组（Ｐ＜０．０５～Ｐ＜０．０１）；ＨｇＣｌ２２．０ｍｇ／ｋｇ体重组肝脏器系数明显高于ＨｇＣｌ２１．０ｍｇ／ｋｇ组和阴性对照组（Ｐ＜０．０１），而肾、脾脏器系数均显著低于ＨｇＣｌ２１．０ｍｇ／ｋｇ体重组和阴性对照组（Ｐ＜０．０５～Ｐ＜０．０１）；精子畸形率也较对照组显著升高（Ｐ＜０．０１）。结论：ＨｇＣｌ２对小鼠具有显著地毒性作用。
Objective: To investigate the toxicity of mercury chloride (HgCl2) to mice. Methods: Toxicology was used to observe the effects of HgCl2 on body weight, organ coefficient and sperm deformity in mice. F test, q test and u test were also performed. Results: The weight gain of HgCl22.0mg / kg and 1.0mg / kg body weight was significantly lower than that of the negative control group (P <0.05 ~ P <0.01); HgCl22.0mg / kg body weight significantly Higher than HgCl21.0mg / kg group and negative control group (P <0.01), while the coefficient of kidney and spleen organs were significantly lower than HgCl21.0mg / kg body weight group and negative control group (P <0.05 ~ P < 0.01). The rate of sperm deformity was also significantly higher than that of the control group (P <0.01). Conclusion: HgCl2 has a significant toxic effect on mice.