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目的分析湖州市无偿献血人群的梅毒感染状况,为无偿献血人员招募和临床安全用血工作提供科学依据。方法对2010年-2014年无偿献血人员的血液样本进行梅毒螺旋体抗体实验室检测。结果 2010年-2014年湖州市无偿献血人群共检测出梅毒抗体阳性748例,阳性率为0.55%(748/135 250)。女性患梅毒的风险是男性的1.22倍(OR=1.22,95%CI:1.05~1.41)。梅毒阳性率随着年龄组的升高而增加,其中30岁~39岁组患梅毒的风险是17岁~29岁组的1.38倍(OR=1.38,95%CI:1.15~1.64),40岁~60岁组患梅毒的风险是17岁~29岁组的1.52倍(OR=1.52,95%CI:1.28~1.80);研究对象在A型、B型、AB型和O型血中的梅毒阳性率分别为0.59%、0.50%、0.58%和0.51%,差异无统计学意义(P>0.05)。结论 2010年-2014年湖州市无偿献血人群梅毒抗体阳性率较2005年-2008年略有上升,应进一步加强梅毒疫情的防控,采取对无偿献血人员的健康宣教和体检征询工作,以保证临床用血安全。
Objective To analyze the status of syphilis infection in blood donors in Huzhou City and provide scientific basis for the recruitment of blood donors and the safety of blood for clinical use. Methods The blood samples of blood donors from 2010 to 2014 were tested in the laboratory of Treponema pallidum antibody. Results A total of 748 cases of syphilis antibody positive were detected in the blood donors from Huazhou in 2010-2014. The positive rate was 0.55% (748/135 250). The risk of developing syphilis was 1.22 times higher in men than in men (OR = 1.22, 95% CI: 1.05-1.41). The positive rate of syphilis increased with the increase of age group. The risk of syphilis among 30-39 age group was 1.38 times (OR = 1.38, 95% CI: 1.15-1.64), 40 years old The risk of syphilis in the age group of 60 years was 1.52-fold (OR = 1.52, 95% CI: 1.28 to 1.80) in the 17-year-old to 29-year-old group; syphilis in type A, B, AB and O blood The positive rates were 0.59%, 0.50%, 0.58% and 0.51%, respectively, with no significant difference (P> 0.05). Conclusion The positive rates of syphilis antibody in blood donors from 2010 to 2014 in Huzhou City increased slightly from 2005 to 2008, the prevention and control of syphilis epidemic should be further strengthened, and the public health education and physical examination of unpaid blood donors should be taken to ensure the clinical Use blood safety.