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目的了解龙岩市健康人群流脑抗体免疫水平,为制订流脑免疫工作计划提供科学依据。方法 2012-2014年采集部分健康人群血清,用酶联免疫吸附试验检测A群和C群流脑抗体水平。结果 3年健康人群A群、C群流脑阳性检出率逐年升高,A群抗体阳性率显著高于C群(χ~2=1 4 5.6 9,P<0.0 1)。A群、C群均无性别间差异。A群抗体水平阳性率随着年龄增加呈上升趋势(χ_(趋势)~2=0.9 5,P>0.0 1)。C群抗体水平3岁~组最高,5岁~组次之,<1岁组A群和C群抗体阳性率均很低。结论龙岩市存在C群流脑暴发的可能,因此要加强C群流脑疫苗的预防接种,要特别关注<1岁组人群。
Objective To understand the immunological level of antibodies against meningococcal encephalitis in healthy population in Longyan City, and to provide a scientific basis for the development of immunization program. Methods Sera from some healthy people were collected from 2012 to 2014. The antibody levels of meningococcal meningitis A and C were detected by enzyme-linked immunosorbent assay (ELISA). Results The positive rate of meningitis in group A and group C increased year by year, and the positive rate of antibody in group A was significantly higher than that in group C (χ ~ 2 = 14.69, P <0.0 1). A group, C group were no gender differences. The antibody positive rate of group A increased with age (χ_ (trend) ~ 2 = 0.9 5, P> 0.0 1). The antibody level of group C was the highest in group 3 years old, followed by group of 5 years old. The positive rate of antibody of group A and group C was very low in <1 year old group. Conclusion There is a possibility of outbreaks of Group C meningitis in Longyan City. Therefore, to strengthen the vaccination of Group C meningitis vaccine, special attention should be paid to the crowd <1 year old.