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以家猪４只行３２磷玻璃徽球（３２ＰＧＭ）肝动脉灌注。实验猪分别处死后病理观察，见肝脏早期有散在的沿小动脉分布的坏死区，３月内坏死区逐渐修复，为新生肝细胞取代。治疗实验用植有Ｈ２２肝癌ＢａｌＢ／Ｃ小鼠４０只作瘤内注射：Ａ组３２ＰＧＭ／甘油混悬液０．２ｍｌ；Ｂ组，无活性玻璃微球／甘油混悬液０．２ｍｌ。两组小鼠平均生存时间分别为２４．８天和１１．８天。Ａ组有５只小鼠存活超过４０天，其中２只小鼠处死时肿瘤已消失。本实验结果提示３２ＰＧＭ对实验性肝癌具有较好的治疗作用。灌注后肝组织损伤与微球不规则分布有关，且可在３月内恢复正常。
4 pigs were treated with 32 PGM hepatic artery perfusion. After experimental pigs were sacrificed and pathologically observed, there were scattered necrotic areas distributed along the small arteries in the early stage of the liver, and the necrotic areas were gradually repaired within 3 months and replaced by neonatal hepatocytes. Therapeutic experiments were performed using intratumoral injection of 40 H22 hepatoma BalB/C mice: Group A 32 PGM/glycerol suspension 0.2 ml; Group B, no active glass microsphere/glycerol suspension 0.2 ml. The average survival time of the two groups of mice was 24.8 days and 11.8 days, respectively. Five mice in group A survived for more than 40 days, and tumors disappeared when 2 mice were sacrificed. The experimental results suggest that 32PGM has a good therapeutic effect on experimental liver cancer. Liver tissue injury after perfusion is related to the irregular distribution of microspheres and can return to normal within 3 months.