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目的：观察无创机械通气治疗老年COPD合并呼吸衰竭的临床疗效。方法：将我院2012年3月至2014年3月收治的68例老年COPD合并呼吸衰竭患者作为研究对象，试验组和对照组各34例，两组在接受常规治疗的同时，试验组患者增加无创机械通气治疗.对比两组患者治疗前后的心率、呼吸频率、动脉血气指标（PaO2、PaCO2）和临床效果。结果：治疗前后各项指标的差异明显，具有统计学意义（P＜0.05）；治疗后试验组患者的心率、呼吸频率和动脉血气指标均优于对照组，两组存在显著差异，具有统计学意义（P＜0.05）；治疗后试验组有效率(82.4%)高于对照组(55.9%)，两组存在显著差异，具有统计学意义（P＜0.05）。结论：无创机械通气治疗老年COPD合并呼吸衰竭的操作简单，疗效显著，建议在临床中推广使用。“,”Objective Observe the clinical effects of non-invasive mechanical ventilation in the treatment of elderly patients with COPD associated with respiratory failure.MethodsDivide the 68 cases of elderly COPD associated with respiratory failure, who received the treatment from Mar.2012 to Mar.2014 into the experimental group and observation group, each group had 34 cases.Both groups received the conventional therapy, and the experimental group received additional treatment of non-invasive mechanical ventilation.Analyze the heart rate, respiratory rate, indexes of arterial blood gas(PaO2、PaCO2)and clinical effect of them.ResultsThe differences of indexes of two groups before and after the treatment were statistically significant(P<0.05); after treatment, heart rate, respiratory rate and indexes of arterial blood gas of experimental group were better than control group(P<0.05);the effective rate of experimental group(82.4%) was higher than control group(P<0.05).ConclusionElderly patients with COPD associated with respiratory failure should be treated with non-invasive mechanical ventilation, as it has easy operation and significant effect.