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【据《Hepatogastroenterology》2014年报道】题:慢加急性肝衰竭患者血浆置换治疗中血氨的变化(作者Ye JL等)慢加急性肝衰竭(AoCLF)病死率高。血浆置换是AoCLF患者内科治疗与肝移植间有效的桥梁。Ye JL等进行了一项研究,目的是评估血浆置换对AoCLF患者血氨水平的影响。本研究共纳入70名AoCLF患者,将其分为2组(血浆置换联合标准药物治疗组32人;标准药物治疗组38人),并分别于入院当天及住院第7、14、21、30 d测定血氨。所有AoCLF患者的血氨水平均超过正常范围的上限。治疗30 d后,存活者中,血浆置换组患者
(Reported by 2014 in Hepatogastroenterology) Title: Changes in Blood Ammonia during Plasma Exchange in Patients with Slow-Acute Liver Failure (by Ye JL, et al) High mortality from Acute Liver Failure (AoCLF). Plasma exchange is an effective bridge between medical treatment and liver transplantation in patients with AoCLF. Ye JL et al conducted a study to assess the effect of plasma exchange on serum ammonia levels in patients with AoCLF. A total of 70 patients with AoCLF were enrolled in this study. They were divided into two groups (plasmapheresis combined with standard drug treatment group of 32; standard drug treatment group of 38 patients), and were on the day of admission and hospitalized 7,14,21,30 d Determination of blood ammonia. Blood ammonia levels in all AoCLF patients exceeded the upper limit of the normal range. After 30 days of treatment, survivors, plasma exchange patients