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目的:通过对余杭区第一人民医院140例的社区获得性肺炎住院病人的病案分析,了解抗菌药物在临床使用中存在的问题,探讨抗菌药物合理使用的策略。方法:采用回顾性分析的方法从本院抽出近3个月的社区获得性肺炎住院病人的病案140例,从限定日剂量(DDD)、药品利用指数(DUI)、住院天数、药品费用等方面分析抗菌药物使用情况。结果:2007年年底到2008年年初,社区获得性肺炎病人抗菌药物的使用率为100%,有12种40%的药品的DUI>1,联合用药比例较高,但总体情况控制较好。常用抗菌药物前三位为氨基糖苷类、β一内酰胺类及其酶抑制药复合制剂和喹诺酮类。结论:抗菌药物的使用在用药剂量、联合用药存在一定的不合理性,医院在对病人的治疗过程中也存在着许多不规范之处。因此,要加强临床医师和药师在抗菌药物合理使用上的指导,以提高临床用药水平。
Objective: To analyze 140 cases of community-acquired pneumonia hospitalized patients in First People’s Hospital of Yuhang District to understand the problems in clinical use of antimicrobial agents and to explore the rational use of antimicrobial agents. Methods: A retrospective analysis of 140 cases of community-acquired pneumonia inpatients was withdrawn from our hospital from the hospital in the last few months. From DDD, DUI, length of hospital stay, cost of medicines and so on Analysis of antimicrobial use. Results: From the end of 2007 to the beginning of 2008, the usage rate of antibacterials in patients with community-acquired pneumonia was 100%. There were 12 kinds of 40% drugs with DUI> 1, the proportion of combination therapy was higher, but the overall control was better. The first three commonly used antibiotics are aminoglycosides, β-lactams and their enzyme inhibitors and quinolones. Conclusion: The use of antimicrobial drugs in the dosage, the combination of medication there is some irrationality, the hospital in the treatment of patients there are many non-standardization. Therefore, to enhance the clinicians and pharmacists in the rational use of anti-bacterial drugs on the guidance to improve the level of clinical medication.