论文部分内容阅读
目的 了解游离Ｆａｓ（ｓＦａｓ）在恶性血液病中的水平及临床意义。方法 用酶联免疫吸附法测定６０ 例恶性血液病患者血清中ｓＦａｓ水平。结果 恶性血液病患者血清ｓＦａｓ水平高于正常人，治疗后ｓＦａｓ水平下降，下降的程度与疗效有关，但治疗前水平高低与疗效无关。结论 ｓＦａｓ对恶性血液病的诊断及疗效判定有一定意义，并可能对其发病机制产生影响。
Objective To investigate the level and clinical significance of free Fas (sFas) in hematological malignancies. Methods The serum levels of sFas in 60 patients with hematologic malignancy were determined by enzyme-linked immunosorbent assay. Results The serum levels of sFas in patients with hematologic malignancies were higher than those in normal subjects. After treatment, the level of sFas was decreased. The degree of decline was related to the efficacy. However, the level of pre-treatment sFas was not related to the efficacy. Conclusions sFas has a certain significance in the diagnosis of hematological malignancy and the determination of its therapeutic effect, and may have an impact on its pathogenesis.