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目的 通过对 30 8例直肠粘液腺癌回顾性分析 ,了解直肠壁肿瘤侵犯的程度与淋巴结转移的关系 ,针对其特点 ,寻求更完善的治疗方案 ,以提高生存率。方法 对 30 8例直肠粘液腺癌病例进行系统整理、归纳 ,分析其病理类型特点。结果 本组病例均为进展期直肠癌 ,发病年龄 18～ 76岁 ,青壮年 (≤ 45岁 )较老年 (>6 0岁 )多见 ,原发灶多位于直肠中下段 ,以浸润型生长为主 ,约 6 5 %侵犯肠腔全周 ,深度至肠壁浆膜层。结论 随着肿瘤侵犯结肠壁的深度增加 ,其局部淋巴结的存在、淋巴结转移的数目、淋巴管侵犯静脉及周围组织受侵犯的危险性逐渐增加。临床上适合行保守性局部切除的患者 ,应代之以根治切除
Objective To analyze the relationship between the extent of invasion of rectal wall tumors and lymph node metastases through a retrospective analysis of 308 rectal mucinous adenocarcinomas, and seek more comprehensive treatment options to improve survival. Methods A total of 308 cases of rectal mucinous adenocarcinoma were systematically summarized and analyzed, and their pathological type characteristics were analyzed. Results The patients in this group were all advanced rectal cancers, and the age of onset was 18-76 years old. Young adults (≤45 years old) were more common than the elderly (>60 years old). The primary tumors were located in the middle and lower rectum, with infiltrative growth as In the main, about 65% of the intestine invaded the entire intestine and depth to the serosa of the intestinal wall. Conclusion With the increased depth of invasion of the colon wall, the presence of local lymph nodes, the number of lymph node metastases, the risk of lymphatic invasion of veins and surrounding tissues are gradually increased. Patients who are clinically suitable for conservative partial resection should be replaced by radical resection