论文部分内容阅读
目的:探讨HBsAg阳性孕产妇的心理应激状况与皮质醇及性激素的关系。方法:随机抽取门诊或住院部就诊的HBsAg(+)妊娠晚期孕产妇67例。采用汉密尔顿抑郁量表(HRSD)、汉密尔顿焦虑量表(HAMA)及症状自评量表(SCL-90)评估HBsAg(+)孕产妇的心理状况;放免法测定血清雌二醇、孕酮及皮质醇水平。结果:抑郁与雌、孕激素水平均呈负相关(P<0.05);焦虑与皮质醇水平呈正相关;症状自评躯体化表现、强迫状态、抑郁和焦虑均与雌激素水平呈负相关(P<0.05);强迫症状和焦虑与皮质醇水平呈正相关。结论:乙肝孕产妇心理健康水平低下与激素水平存在相关性,血浆皮质醇及性激素水平是评估其心理状态的有效指标。
Objective: To investigate the relationship between psychological stress and cortisol and sex hormones in HBsAg-positive pregnant women. Methods: Sixty-seven pregnant women with HBsAg (+) at the third trimester of pregnancy were selected randomly from outpatients or inpatients. The psychological status of HBsAg (+) pregnant women was evaluated by Hamilton Depression Rating Scale (HAMA) and Symptom Checklist 90 (SCL-90). Serum estradiol, progesterone and cortex Alcohol level. Results: There was a negative correlation between depression and estrogen and progesterone levels (P <0.05). There was a positive correlation between anxiety and cortisol levels. Symptom self-assessment of somatization, coercion, depression and anxiety were negatively correlated with estrogen levels (P <0.05). Forced symptoms and anxiety were positively correlated with cortisol levels. Conclusion: There is a correlation between the low level of mental health of pregnant women and the level of hormone. The level of plasma cortisol and sex hormone is an effective index to evaluate their psychological status.