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目的:观察关于急性有机磷农药中毒后采用留置胃管反复洗胃联合甘露醇胃管注入导泻治疗的临床效果。方法:选择2011年3月-2014年2月贵州航天医院收治的急性有机磷中毒患者112例,随机分为观察组与对照组,每组56例。对照组患者给予温清水彻底洗胃,阿托品、解磷定及综合治疗,并留置胃管予生理盐水间断反复洗胃,观察组在对照组的基础上加用甘露醇导泻,对比对照组和观察组阿托品的用量、住院时间及并发症发生率。结果:观察组在阿托品用量、住院时间等方面均明显优于对照组,差异有统计学意义(P<0.05),观察组并发症发生率为5.4%,而对照组并发症发生率为17.9%,差异有统计学意义(P<0.05)。结论:有机磷农药中毒患者经彻底洗胃后,留置胃管反复洗胃并联合甘露醇导泻治疗,能明显减少阿托品用量、缩短住院时间、减少并发症的发生。
OBJECTIVE: To observe the clinical effect of repeated gastric lavage combined with mannitol and gastric tube infusion after catheterization in patients with acute organophosphorus pesticide poisoning. Methods: One hundred and twelve patients with acute organophosphate poisoning who were treated in Guizhou Aerospace Hospital from March 2011 to February 2014 were randomly divided into observation group and control group with 56 cases in each group. Patients in the control group were given warm water thoroughly gastric lavage, atropine, phosphate solution and comprehensive treatment, and left gastric tube intermittent gastric lavage repeated gastric lavage, the observation group in the control group based on the use of mannitol catharsis, compared with the control group and Observation group atropine dosage, length of stay and complication rates. Results: The observation group was significantly better than the control group in the amount of atropine and hospital stay, the difference was statistically significant (P <0.05), the incidence of complications in the observation group was 5.4%, while the incidence of complications in the control group was 17.9% , The difference was statistically significant (P <0.05). Conclusion: After thoroughly gastric lavage, patients with organophosphorus pesticide poisoning, gastric lavage with repeated gastric lavage and mannitol catharsis treatment can significantly reduce the amount of atropine, shorten the hospital stay and reduce the incidence of complications.