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已知在原发性肾小球肾炎(GN)的肾活检标本尤其是含有硬化肾小球的标本中可以观察到肾小管间质损害(TIL),然而这类损害有时常被忽视或认为意义不大。作者对成人GN的常见类型作了回顾性研究,以评价TIL在估计GN的严重性和预后方面的意义。本研究包括IgA肾病(IgA-N)101例,IgA阴性的增殖性肾炎(PGN)31例,特发性膜性肾小球肾炎(IMGN)75例。平均随访时间为72个月。对上述病例的肾活检标本作了常规染色及检
Tubulointerstitial lesions (TILs) are known to be observed in renal biopsy specimens of primary glomerulonephritis (GN), especially those with sclerosing glomeruli, however such lesions are sometimes overlooked or found to be of significance Not big. The authors made a retrospective study of common types of adult GN to assess the significance of TIL in estimating the severity and prognosis of GN. This study included 101 cases of IgA nephropathy (IgA-N), 31 cases of IgA-negative proliferative glomerulonephritis (PGN) and 75 cases of idiopathic membranous glomerulonephritis (IMGN). The average follow-up time was 72 months. The above cases of renal biopsy specimens were routinely stained and seized