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异位妊娠常规手术后有相当多的继发性不孕和腹部手术的常见危险。妊娠妇女全身性使用前列腺(PG)类药物能终止妊娠;继续异位妊娠的数字较预计值也少。作者以前有关PG对人体输卵管平滑肌包括血管作用的研究结果已清楚表明PGF类与其它PG相反,总可引起较强的收缩。体外试验也表明PGF_(2a)有抗促性腺激素的作用。这些均提示PGF类对某些异位妊娠的治疗有效。作者报告了有关临床试验即局部注射PGF_(2a)可降低副作用如呕吐、腹泻,又可增加附件局部的药物浓度。受试者为9例25~32岁异位妊娠妇女,均符合下列条件:血清绒毛膜促性腺激素(hCG)≥50IU/L。含血的受损输卵管扩张。腹腔内绒毛膜组织学检查或子宫腔刮出物中无绒毛膜组织。试验不
There are quite a few common risks of secondary infertility and abdominal surgery after conventional surgery for ectopic pregnancy. Pregnancy Women Systemic Prostate (PG) Drugs Terminate Pregnancy; Continued Ectopic Pregnancy Numbers More Than Expected. Previous studies by the author on the effects of PG on the vascular function of human fallopian tube smooth muscle have clearly demonstrated that PGFs, in contrast to other PGs, always cause a stronger contraction. In vitro experiments also showed that PGF_ (2a) has anti-gonadotropin effect. These all suggest that the PGF class is effective in the treatment of some ectopic pregnancies. The authors report that the clinical trial that topical injection of PGF_ (2a) reduces side effects such as vomiting and diarrhea, as well as increasing the local drug concentration in the attachment. Subjects were 9 ectopic pregnancy women aged 25 to 32, all of which met the following criteria: serum chorionic gonadotropin (hCG) ≥ 50IU / L. Bloody damaged tubal dilatation. Abdominal chorionic histology or uterine cavity scraping material without chorionic tissue. Test not